The Frailty Syndrome Article Published Online

An article on the frailty syndrome, authored by M. Jane Mohler, Mindy J. Fain, Anne M. Wertheimer, Bijan Najafi, and Janko Nikolich-Žugich, has been published in Experimental Gerontology, Volume 54, June 2014, Pages 6–13.

The article is available online from ScienceDirect.


  • There is a lack of fundamental understanding and of animal models to study frailty.
  • We discuss key theories of frailty—cytokine dysfunction and mitochondrial disorder.
  • There is a need for objective human measures using biosensors and imaging.
  • We review recent breakthroughs correlating animal and human frailty measures.
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Sunday, June 1, 2014 - 12:00